News – Scientists discover genes that protect the brain from aging

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This study sheds light on the effect of the gene on the aging of brain cells. Researchers say that exercise in particular promotes the production of this gene

U.S. biologists have found that the gene protects brain stem cells from aging, reports Weil Medical College

An abnormal version of this gene, called FOXO3, has already been found in most people over 100 years of age. American researchers have now discovered that this gene is involved in the reproduction of brain stem cells. Their study was published in the journal Nature Communications

The effects of the FOXO3 gene have been demonstrated experimentally in mice. Researchers have found that models without FOXO3 do not tolerate oxidative stress, which can lead to progressive brain death. The gene inhibits stem cell division, especially by its action on the nutrient S-adenosylmethionine (SAM)

This new study also identified a link between mental sharpness and regular exercise, the latter of which specifically stimulates FOXO3 production in the body. Their work will help to understand how this gene is linked to longevity, scientists’ It’s too early to talk about new treatments for brain disease

Scientists are now working in this direction and studying how to better control the FOXO3 gene or briefly turn it on and off.

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